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Table 3 Nucleotide differences between wild type parental and biologically cloned virus.

From: Genome sequence analysis of La Crosse virus and in vitro and in vivo phenotypes

LACV Virus Nucleotide substitution in indicated LACV segmenta
human/1960-clone A525T A503Gb A1837G
   C2221T  
human/1978-clone No changesc T391C No changes
   A1636G  
   A1929Gb  
mosquito/1978-clone A719Gb No changes A31G
    G33A
  1. aParental nucleotide on left, nucleotide substitution in the cloned virus on right.
  2. bIndicates a nucleotide substitution resulting in an amino acid substitution.
  3. cParental and cloned virus have identical sequences.