Skip to main content

Advertisement

Table 3 MCMV nPCR for fetuses from SCID dams injected with 103 PFU of MCMV at E4.

From: Transplacental murine cytomegalovirus infection in the brain of SCID mice

E12 MCMV Litters
SCID DAM Litter Size Negative Fetuses (Brain-/Viscera-) Positive Fetuses (Brain+or Viscera+) Brain+Fetuses (Brain+or Viscera+)a
1 4 4 (100%) 0 (0%) *
2 7 7 (100%) 0 (0%) *
5 4 4 (100%) 0 (0%) *
4 9 2 (22%) 7 (78%) *
5 5 1 (20%) 4 (80%) *
Total 29 18 (62%) 11 (38%) *
E14 MCMV Litters
1 4 3 (75%) 1 (25%) 1 (25%)
2 3 0 (0%) 3 (100%) 1 (33%)
3 2 1 (50%) 1 (50%) 0 (0%)
4 8 2 (25%) 6 (75%) 3 (38%)
5 7 6 (86%) 1 (14%) 0 (0%)
Total 24 12 (50%) 12 (50%) 5 (21%)
E16 MCMV Litters
1 5 4 (80%) 1 (20%) 1 (20%)
2 6 1 (16%) 5 (84%) 2 (33%)
3 6 5 (83%) 1 (17%) 0 (0%)
4 7 7 (100%) 0 (0%) 0 (0%)
5 4 4 (100%) 0 (0%) 0 (0%)
6 4 3 (75%) 1 (25%) 0 (0%)
Total 32 24 (75%) 8 (25%) 3 (10%)
E18 MCMV Litters
1 8 7 (86%) 1 (14%) 0 (0%)
2 3 0 (0%) 3 (100%) 3 (100%)
3 5 0 (0%) 5 (100%) 3 (60%)
4 7 4 (57%) 3 (43%) 0 (0%)
5 7 2 (29%) 5 (71%) 1 (14%)
6 3 1 (33%) 2 (67%) 0 (0%)
7 5 3 (60%) 2 (40%) 1 (20%)
8 5 3 (60%) 2 (40%) 1 (20%)
9 3 0 (0%) 3 (100%) 1 (33%)
10 5 3 (60%) 2 (40%) 0 (0%)
11 5 2 (40%) 3 (60%) 0 (0%)
12 3 2 (67%) 1 (33%) 0 (0%)
13 10 7 (70%) 3 (30%) 0 (0%)
14 9 0 (0%) 9 (100%) 5 (56%)
15 10 7 (70%) 3 (30%) 0 (0%)
16 6 3 (50%) 3 (50%) 1 (17%)
Total 94 44 (47%) 50 (53%) 16 (17%)
  1. *: Whole body nPCR assayed to detect MCMV DNA at E12 due to the small size of the fetus.
  2. a: All nPCR brain+ fetuses were also nPCR viscera+.