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Figure 2 | Virology Journal

Figure 2

From: Role of HIV-1 subtype C envelope V3 to V5 regions in viral entry, coreceptor utilization and replication efficiency in primary T-lymphocytes and monocyte-derived macrophages

Figure 2

Replication of HIV-1 subtype C env V3–V5 region chimeras in T-lymphocyte (A3.01) cell line. A3.01 cells (1 × 106 cells/well) were infected with equal amounts (RT counts) subtype C env chimeras (171 to 1014), parental HIV-1NL4-3 and HIV-1BaL. Virus production was measured by reverse transcriptase (RT) assay in culture media harvested every 3 days and the cells fed with appropriate media. The results are presented as cpm/ml ± SD of five separate triplicate experiments. The subtype C chimeras were unable to replicate in A3.01 cell line.

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Virology Journal

ISSN: 1743-422X