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Figure 6 | Virology Journal

Figure 6

From: The E5 protein of the human papillomavirus type 16 down-regulates HLA-I surface expression in calnexin-expressing but not in calnexin-deficient cells

Figure 6

Transmembrane Hidden Markov Model posterior probabilities for the sequences of E5 and the mutants M1, M2 and M3. A) Amino acid sequence of the wild-type E5 protein and corresponding mutants. Aminoacids of the AU1-tag are underlined. Arrows show the position of exchanged amino acids. B) Analysis of the wild-type E5 and mutants using the TMHMM 2.0 algorithm (36, 37), showing the three hydrophobic regions predicted to be transmembrane domains, and the corresponding disruptions in the three mutants.

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Virology Journal

ISSN: 1743-422X