Weight loss, viremia and serum chemistry values of mice infected with 'scid-adapted' MARV. Scid mice were infected with 1000 pfu of the indicated 'scid-adapted' MARV (Ci67 P15, Musoke P10 or Ravn P10). (A) The weight of groups of 10 mice was assessed daily after infection with the 'scid-adapted' MARV. The data are expressed as the average weight of the mice in each group. (B) Viral titers were measured using standard plaque assay on serum samples obtained from terminal cardiac punctures of infected mice on 0, 2, 4, 6 or 8 days postinfection. Levels of (C) Blood urea nitrogen (BUN), (D) glucose (E) alanine transaminase (ALT), and (F) aspartate transaminase (AST) were measured at the indicated timepoints using serum collected by terminal cardiac puncture. Data for panels B-F are expressed as the average of values from four to five mice/timepoint and error bars indicate the standard deviation.