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Figure 5 | Virology Journal

Figure 5

From: Porcine reproductive and respiratory syndrome virus (PRRSV) infection spreads by cell-to-cell transfer in cultured MARC-145 cells, is dependent on an intact cytoskeleton, and is suppressed by drug-targeting of cell permissiveness to virus infection

Figure 5

Two-color fluorescence detection of actin (red) and PRRSV antigen (green) in MARC-145 cells. A. Uninfected control, 20 μm; B.18 h p.i. with PRRSV, 20 μm; C. Control at 42 h p.i. with PRRSV, 50 μm; D. Drug vehicle control at 42 h p.i. with PRRSV, 50 μm. E. Colchicine-treated, 5 μM, 42 h p.i. (arrow indicates PRRSV-positive doublet; see Figure 6, A, C and D for higher magnification), 50 μm; F. AK-2 treated, 250 μm; (Length of scale bar is indicated for each panel)

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