Figure 3From: Porcine reproductive and respiratory syndrome virus (PRRSV) infection spreads by cell-to-cell transfer in cultured MARC-145 cells, is dependent on an intact cytoskeleton, and is suppressed by drug-targeting of cell permissiveness to virus infectionConfocal microscopy of FA-stained MARC-145 cells during PRRSV infection. A. 24 h p.i. with PRRSV, 20 μm.; B-C. Secondary cluster formation (arrows) 42–46 h p.i. with PRRSV, 20 μm; D. Secondary cluster formation (arrow) 72 h p.i. with PRRSV, 20 μm.; E. AK-2 pretreatment, 42 h p.i.; arrow indicates a single PRRSV-positive cell, 50 μm; F. AK-2 post-treatment, 46 h p.i., arrows indicate several PRRSV-positive clusters, 20 μm. (Length of scale bar is indicated for each panel)Back to article page