Mutants | HFFs | Gingival Tissue |
---|
TowneBAC | +++ | +++ |
ΔUL13 | +++ | ++ |
ΔUL24 | +++ | +++ |
ΔUL25 | +++ | +++ |
ΔUL108 | +++ | +++ |
ΔUS18 | +++ | + |
ΔUS20 | +++ | +++ |
ΔUS29 | +++ | +++ |
ΔRL9 | +++ | +++ |
- Cells (1 × 106 HFFs) or tissues were infected with each virus at 2 × 104 PFU and at 10 days post-infection, cells and tissues were harvested and sonicated. The viral titers were determined by plaque assays on HFFs in triplicate experiments [46]. +++, titer similar to that of TowneBAC; ++, titer about 10 times lower than that of TowneBAC; +, titer at least 100 times lower than that of TowneBAC.