Figure 5
From: Caveolin-1 interacts with the Gag precursor of murine leukaemia virus and modulates virus production
Effect of CBD expression on MLV production. Expression plasmids carrying cloned caveolin-1 binding domains were transfected into 4070A infected NIH3T3 cells and the effect on virus release was determined by infectious titer assay as described in Material and Methods. Competition experiments involved the putative CBD domain in MA of MLVs or a consensus CBD derived from display analysis [27].