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Table 6 T-cell responses for subjects grouped by HSV-1/HSV-2 serostatus. Data is the same as Table 2 but subjects have been organized into groups based on their HSV-1 and HSV-2 serostatus. For CD4 responses, the total number of ELISPOTs (E#) for each peptide pool of that group is included. Total number of CD4 ELISPOTs for each protein from each group were used to generate a ratio of the ELISPOTs measured in HSV-1/HSV-2 double positives and HSV-2 single positives. Values were adjusted to compensate for the different number of subjects per group

From: Characterization of the IFN-γ T-cell responses to immediate early antigens in humans with genital herpes

HSV-2 SINGLE POSITIVIES
CD4 Responses CD8 Responses
Patient ICP27 ICP22 ICP0–1 ICP0–2 ICP0–3 ICP4–1 ICP4–2 ICP4–3 ICP4–4 ICP4–5 ICP4–6 VP22 gD   ICP0 ICP4 VP22
6 W W   S   W W   W    S S     
8   W S      W   W   W W   P   
9 W    S   W   S   S   W W   P P  
11 W W      W W     S S     
12   S S   W   W W   S   S S     
14              S     P
15   W S      W   W W S S     P
16    W      S     W S     
E# 37 87 133 62 21 14 18 135 62 69 8 309 394     
HSV-2/HSV-1 DOUBLE POSITIVES
CD4 Responses CD8 Responses
Patient ICP27 ICP22 ICP0–1 ICP0–2 ICP0–3 ICP4–1 ICP4–2 ICP4–3 ICP4–4 ICP4–5 ICP4–6 VP22 gD   ICP0 ICP4 VP22
1 S S       W W W W S W     
2    W      S   S   W S     P
3 W    S      S S S S S    P  
5 W W    S     W     S   P   P
13      S        S S     
18   W   S    W W S   S S W    P  
E# 64 45 23 96 96 0 9 128 96 109 64 261 254     
HSV-1 SINGLE POSITIVES
CD4 Responses CD8 Responses
Patient ICP27 ICP22 ICP0–1 ICP0–2 ICP0–3 ICP4–1 ICP4–2 ICP4–3 ICP4–4 ICP4–5 ICP4–6 VP22 gD   ICP0 ICP4 VP22
7         S   W        
10      W      S        
17         S   S        
      7    152   130        
  ICP27 ICP22 ICP0 ICP4 VP22 gD            
  2.4 0.68 1.3 1.5 1.1 0.86 Ratio of double positive/HSV-2 single positive