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Figure 2 | Virology Journal

Figure 2

From: The synergistic effect of IFN-α and IFN-γ against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin

Figure 2

Treatment with IFN protects HSV-2 infected cells from viral cytopathic effect. (a) Uninfected cells per culture that remained viable at different times after treatment with (■) vehicle, (●) 100 IU/ml IFN-α, (▲) 100 IU/ml IFN-γ, () 100 IU/ml each of IFN-α and IFN-γ, (▼) CDM, (◆) CDM + IFN-α, (+) CDM + IFN-γ and () CDM + IFN-α and IFN-γ. (b) Number of MS-infected cells that remained viable at times after inoculation in the presence of (■) vehicle, (●) 100 IU/ml IFN-α, (▲) 100 IU/ml IFN-γ or (▼) 100 IU/ml each of IFN-α and IFN-γ. (c) Number of MS-infected cells that remained viable at times after inoculation in the presence of (■) CDM, (●) CDM + 100 IU/ml IFN-α, (▲) CDM + 100 IU/ml IFN-γ or (▼) CDM + 100 IU/ml each of IFN-α and IFN-γ.). One-way ANOVA followed by Tukey's post hoc t test confirmed that the differences were significant (p < 0.001).

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Virology Journal

ISSN: 1743-422X