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Figure 3 | Virology Journal

Figure 3

From: Nectin-2-mediated entry of a syncytial strain of herpes simplex virus via pH-independent fusion with the plasma membrane of Chinese hamster ovary cells

Figure 3

CHO cell entry pathways of HSV-1 rid1 and ANG path mediated by nectin-2. CHO-nectin-2 (A, C) or CHO-nectin-1 cells (B) were treated with the indicated concentrations of wortmannin (A, B) or monensin (C) for 30 min. HSV-1 strains rid1 or ANG path were added (MOI of 1) for 6 h in the continued presence of agent. Entry (beta-galactosidase activity) was measured as in the legend to Figure 2.

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