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Figure 6 | Virology Journal

Figure 6

From: The role of cholesterol and sphingolipids in chemokine receptor function and HIV-1 envelope glycoprotein-mediated fusion

Figure 6

Chemokine-Triggered Ca2+ Mobilization. Intracellular Ca2+ mobilization was measured by stimulating Fura-2 loaded NIH3T3CD4CXCR4 (A) or NIH3T3CD4CCR5 (B) cells with chemokines SDF1-α (A) or MIP1-β (B) at different concentrations. The ratio of fluorescence at 340 and 380 nm was calculated using a FL Win Lab program (Perkin-Elmer). Left panel: untreated cells, middle panel: PPMP-treated cells; right panel: MβCD-treated cells.

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