Figure 1From: RETRACTED ARTICLE: Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypesLocation of siRNA targets to the 5'UTR of HCV genome. Predicted secondary structure of the 5' UTR sequences (18–357). The sequence shown is that of the genotype 1a 5'UTR, HCV-H [40], and the structure based on previous studies [41-43]. Stem-loop structures are labeled for reference. The chimeric clones were made by fusing the GFP-encoding sequence, including a poly (A) tail, after the CCU sequence of the 5'UTR by overlapping PCR. The locations of siRNA targets in the stem-loop regions are shown by arrows.Back to article page