TY - JOUR AU - Choo, Q. L. AU - Kuo, G. AU - Weiner, A. J. AU - Overby, L. R. AU - Bradley, D. W. AU - Houghton, M. PY - 1989 DA - 1989// TI - Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome JO - Science VL - 244 UR - https://doi.org/10.1126/science.2523562 DO - 10.1126/science.2523562 ID - Choo1989 ER - TY - JOUR AU - Alter, M. J. PY - 1997 DA - 1997// TI - Epidemiology of hepatitis C JO - Hepatology VL - 26 UR - https://doi.org/10.1002/hep.510260711 DO - 10.1002/hep.510260711 ID - Alter1997 ER - TY - JOUR PY - 2000 DA - 2000// TI - Hepatitis C: global prevalence (update) JO - Wkly Epidemiol Rec VL - 75 ID - ref3 ER - TY - JOUR AU - Theodore, D. AU - Fried, M. W. PY - 2000 DA - 2000// TI - Natural history and disease manifestations JO - Curr Top Microbiol VL - 242 ID - Theodore2000 ER - TY - JOUR AU - Alter, H. J. AU - Seeff, L. B. PY - 2000 DA - 2000// TI - Recovery, persistence and sequelae in hepatitis C virus infection: a perspective on long-term outcome JO - Seminar Liver Disease VL - 20 UR - https://doi.org/10.1055/s-2000-9505 DO - 10.1055/s-2000-9505 ID - Alter2000 ER - TY - JOUR AU - Davis, G. L. PY - 2000 DA - 2000// TI - Current therapy for chronic hepatitis C JO - Gastroenterology VL - 118 UR - https://doi.org/10.1016/S0016-5085(00)70009-6 DO - 10.1016/S0016-5085(00)70009-6 ID - Davis2000 ER - TY - JOUR AU - Davis, G. L. AU - Esteban-Mur, R. AU - Rustgi, V. AU - Hoefs, J. AU - Gordon, S. C. AU - Trepo, C. AU - Shiffman, M. L. AU - Zeuzem, S. AU - Craxi, A. AU - Ling, M. H. AU - Albrecht, J. PY - 1998 DA - 1998// TI - Interferon alfa-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group JO - N Engl J Med VL - 339 UR - https://doi.org/10.1056/NEJM199811193392102 DO - 10.1056/NEJM199811193392102 ID - Davis1998 ER - TY - JOUR AU - Liang, T. J. AU - Rehermann, B. AU - Seeff, L. B. AU - Hoofnagle, J. H. PY - 2000 DA - 2000// TI - Pathogenesis, natural history, treatment, and prevention of hepatitis C JO - Ann Intern Med VL - 132 UR - https://doi.org/10.7326/0003-4819-132-4-200002150-00008 DO - 10.7326/0003-4819-132-4-200002150-00008 ID - Liang2000 ER - TY - JOUR AU - Dash, S. AU - Prabhu, R. AU - Hazari, S. AU - Bastian, F. AU - Garry, R. F. AU - Zou, W. AU - Haque, S. AU - Joshi, V. AU - Regenstein, F. G. AU - Thung, S. N. PY - 2005 DA - 2005// TI - Interferons alpha, beta, gamma each inhibits hepatitis C virus replication at the level internal ribosome entry site mediated translation JO - Liver International VL - 25 UR - https://doi.org/10.1111/j.1478-3231.2005.01082.x DO - 10.1111/j.1478-3231.2005.01082.x ID - Dash2005 ER - TY - JOUR AU - Miller, R. H. AU - Purcell, R. H. PY - 1990 DA - 1990// TI - Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups JO - Proc Natl Acad Sci(USA) VL - 87 UR - https://doi.org/10.1073/pnas.87.6.2057 DO - 10.1073/pnas.87.6.2057 ID - Miller1990 ER - TY - JOUR AU - Reed, K. E. AU - Rice, C. M. PY - 2000 DA - 2000// TI - Overview of hepatitis C virus genome structure, polyprotein processing and protein properties JO - Curr Top Microbiol Immunol VL - 242 ID - Reed2000 ER - TY - JOUR AU - Friebe, P. AU - Lohmann, V. AU - Krieger, N. AU - Bartenschalager, R. PY - 2001 DA - 2001// TI - Sequences in the 5' Nontranslated Region of Hepatitis C Virus Required for RNA Replication JO - J Virol VL - 75 UR - https://doi.org/10.1128/JVI.75.24.12047-12057.2001 DO - 10.1128/JVI.75.24.12047-12057.2001 ID - Friebe2001 ER - TY - JOUR AU - Friebe, P. AU - Bartenschlager, R. PY - 2002 DA - 2002// TI - Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication JO - J Virol VL - 76 UR - https://doi.org/10.1128/JVI.76.11.5326-5338.2002 DO - 10.1128/JVI.76.11.5326-5338.2002 ID - Friebe2002 ER - TY - JOUR AU - Wilson, J. A. AU - Jayasena, S. AU - Khvorova, A. AU - Sabatinos, S. AU - Rodrigue-Gervaia, I. G. AU - Arya, S. AU - Sarangi, F. AU - Harris-Brandts, M. AU - Beaulieu, S. AU - Richardson, C. D. PY - 2003 DA - 2003// TI - RNA interference blocks gene expression and RNA synthesis from hepatitis C replicon propagated in human liver cells JO - Proc Natl Acad Sci (USA) VL - 100 UR - https://doi.org/10.1073/pnas.252758799 DO - 10.1073/pnas.252758799 ID - Wilson2003 ER - TY - JOUR AU - Kapadia, S. B. AU - Brideau-Andersen, A. AU - Chisari, F. V. PY - 2003 DA - 2003// TI - Interference of hepatitis C virus RNA replication by short interfering RNAs JO - Proc Natl Acad Sci (USA) VL - 100 UR - https://doi.org/10.1073/pnas.252783999 DO - 10.1073/pnas.252783999 ID - Kapadia2003 ER - TY - JOUR AU - Randall, G. AU - Grakoui, A. AU - Rice, C. M. PY - 2003 DA - 2003// TI - Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs JO - Proc Natl Acad Sci VL - 100 UR - https://doi.org/10.1073/pnas.0235524100 DO - 10.1073/pnas.0235524100 ID - Randall2003 ER - TY - JOUR AU - Seo, M. Y. AU - Abrignan, S. AU - Houghton, M. AU - Han, J. H. PY - 2003 DA - 2003// TI - Small interfering RNA- mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7 JO - J Virol VL - 77 UR - https://doi.org/10.1128/JVI.77.1.810-812.2003 DO - 10.1128/JVI.77.1.810-812.2003 ID - Seo2003 ER - TY - JOUR AU - Sen, A. AU - Steele, R. AU - Ghosh, A. K. AU - Basu, A. AU - Ray, R. AU - Ray, R. B. PY - 2003 DA - 2003// TI - Inhibition of hepatitis C virus protein expression by RNA interference JO - Virus Research VL - 96 UR - https://doi.org/10.1016/S0168-1702(03)00170-9 DO - 10.1016/S0168-1702(03)00170-9 ID - Sen2003 ER - TY - JOUR AU - Yokota, T. AU - Sakamoto, N. AU - Enomoto, N. AU - tanabe, Y. AU - Miyagishi, M. AU - Maekawa, S. AU - Yi, L. AU - Kurosaki, M. AU - Taira, K. AU - Watanabe, M. AU - Mizusawa, H. PY - 2003 DA - 2003// TI - Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs JO - EMBO J VL - 4 UR - https://doi.org/10.1038/sj.embor.embor840 DO - 10.1038/sj.embor.embor840 ID - Yokota2003 ER - TY - JOUR AU - Kronke, J. AU - Kittler, R. AU - Buchholtz, F. AU - Windisch, M. P. AU - Pietschmann, T. AU - Bartenschalager, R. AU - Frese, M. PY - 2004 DA - 2004// TI - Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs JO - J Virol VL - 78 UR - https://doi.org/10.1128/JVI.78.7.3436-3446.2004 DO - 10.1128/JVI.78.7.3436-3446.2004 ID - Kronke2004 ER - TY - JOUR AU - Prabhu, R. AU - Vittal, P. AU - Yin, Q. AU - Flemington, E. AU - garry, R. F. AU - Robichaux, W. H. AU - Dash, S. PY - 2005 DA - 2005// TI - Small interfering RNA effectively inhibits protein expression and negative strand RNA synthesis from a full-length hepatitis C virus clone JO - J Med Virol VL - 76 UR - https://doi.org/10.1002/jmv.20391 DO - 10.1002/jmv.20391 ID - Prabhu2005 ER - TY - JOUR AU - Simmonds, P. PY - 2004 DA - 2004// TI - Genetic diversity and evolution of hepatitis C virus–15 years on JO - J Gen Virol VL - 85 UR - https://doi.org/10.1099/vir.0.80401-0 DO - 10.1099/vir.0.80401-0 ID - Simmonds2004 ER - TY - JOUR AU - Simmonds, P. AU - Mellor, J. AU - Sakuldamrongpanich, T. AU - Nuchaprayoon, C. AU - Tanprasert, S. AU - Holmes, E. C. AU - Smith, D. B. PY - 1996 DA - 1996// TI - Evolutionary analysis of variants of hepatitis C virus found in South East Asia: comparison with classifications based upon sequence similarity JO - J Gen Virol VL - 77 UR - https://doi.org/10.1099/0022-1317-77-12-3013 DO - 10.1099/0022-1317-77-12-3013 ID - Simmonds1996 ER - TY - JOUR AU - Bukh, J. AU - Miller, R. H. AU - Purcell, R. H. PY - 1995 DA - 1995// TI - Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes JO - Semin Liver Dis VL - 15 UR - https://doi.org/10.1055/s-2007-1007262 DO - 10.1055/s-2007-1007262 ID - Bukh1995 ER - TY - JOUR AU - Alter, M. J. AU - Kruszon-Moran, D. AU - Nainan, O. V. AU - McQuillan, G. M. AU - Gao, F. AU - Moyer, L. A. AU - Kaslow, R. A. AU - Margolis, H. S. PY - 1999 DA - 1999// TI - The prevalence of hepatitis C virus infection in the United States, 1988 through 1994 JO - N Engl J Med VL - 341 UR - https://doi.org/10.1056/NEJM199908193410802 DO - 10.1056/NEJM199908193410802 ID - Alter1999 ER - TY - JOUR AU - Yanagi, M. AU - Purcell, R. H. AU - Emerson, S. U. AU - Bukh, J. PY - 1997 DA - 1997// TI - Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected in to the livers of a chimpanzee JO - Proc Natl Acad Sci (USA) VL - 94 UR - https://doi.org/10.1073/pnas.94.16.8738 DO - 10.1073/pnas.94.16.8738 ID - Yanagi1997 ER - TY - JOUR AU - Yanagi, M. AU - Claire, M. S. AU - Shapiro, M. AU - Emerson, S. U. AU - Purcell, R. H. AU - Bukh, J. PY - 1998 DA - 1998// TI - Transcripts of a chimeric clone of hepatitis C virus genotype 1b are infectious in vivo JO - Virology VL - 244 UR - https://doi.org/10.1006/viro.1998.9092 DO - 10.1006/viro.1998.9092 ID - Yanagi1998 ER - TY - JOUR AU - Dash, S. AU - Kalkeri, G. AU - McClure, H. M. AU - Garry, R. F. AU - Clejan, S. AU - Thung, S. N. AU - Murthy, K. K. PY - 2001 DA - 2001// TI - Transmission of HCV to a chimpanzee using virus particles produced in an RNA transfected hepG2 cell culture JO - J Med Virol VL - 65 UR - https://doi.org/10.1002/jmv.2030 DO - 10.1002/jmv.2030 ID - Dash2001 ER - TY - JOUR AU - De Francesco, R. AU - Rice, C. M. PY - 2003 DA - 2003// TI - New therapies on the horizon for hepatitis C: are we close JO - Clinics Liver Dis VL - 7 UR - https://doi.org/10.1016/S1089-3261(02)00069-7 DO - 10.1016/S1089-3261(02)00069-7 ID - De Francesco2003 ER - TY - JOUR AU - Cullen, B. R. PY - 2002 DA - 2002// TI - interference: anti-viral defense and genetic cool JO - Nat Immune VL - 3 UR - https://doi.org/10.1038/ni0702-597 DO - 10.1038/ni0702-597 ID - Cullen2002 ER - TY - JOUR AU - Hannon, G. J. PY - 2002 DA - 2002// TI - RNA interference JO - Nature VL - 418 UR - https://doi.org/10.1038/418244a DO - 10.1038/418244a ID - Hannon2002 ER - TY - JOUR AU - Dykxhoorn, D. M. AU - Palliser, D. AU - Lieberman, J. PY - 2006 DA - 2006// TI - The silent treatment: siRNAs as small molecule drug JO - Gene Ther VL - 13 UR - https://doi.org/10.1038/sj.gt.3302703 DO - 10.1038/sj.gt.3302703 ID - Dykxhoorn2006 ER - TY - JOUR AU - Lindenbach, B. D. AU - Rice, C. M. PY - 2002 DA - 2002// TI - RNAi targeting an animal virus: news from the front JO - Mol Cell VL - 9 UR - https://doi.org/10.1016/S1097-2765(02)00539-7 DO - 10.1016/S1097-2765(02)00539-7 ID - Lindenbach2002 ER - TY - JOUR AU - Joost Haasnoot, P. C. AU - Cupac, D. AU - Barkhout, B. PY - 2003 DA - 2003// TI - Inhibition of virus replication by RNA intereference JO - J Biomed Sci VL - 10 UR - https://doi.org/10.1159/000073526 DO - 10.1159/000073526 ID - Joost Haasnoot2003 ER - TY - JOUR AU - Bukh, J. AU - Purcell, R. H. AU - Miller, R. H. PY - 1992 DA - 1992// TI - Sequence analysis of the 5' non-coding region of hepatitis C virus JO - Proc Natl Acad Sci (USA) VL - 89 UR - https://doi.org/10.1073/pnas.89.11.4942 DO - 10.1073/pnas.89.11.4942 ID - Bukh1992 ER - TY - JOUR AU - Hazari, S. AU - Patil, A. AU - Joshi, V. AU - Sullivan, D. AU - Fermin, C. D. AU - Garry, R. F. AU - Elliott, R. M. AU - Dash, S. PY - 2005 DA - 2005// TI - Alpha interferon inhibits translation mediated by the internal ribosome entri site of six different hepatitis C virus genotypes JO - J Gen Virol VL - 86 UR - https://doi.org/10.1099/vir.0.81132-0 DO - 10.1099/vir.0.81132-0 ID - Hazari2005 ER - TY - JOUR AU - Myung, J. AU - Khalap, N. AU - Kalkeri, G. AU - Garry, R. AU - Dash, S. PY - 2001 DA - 2001// TI - Inducible model to study negative strand RNA synthesis and assembly of hepatitis C virus from a full-length cDNA clone JO - J Virol Meth VL - 94 UR - https://doi.org/10.1016/S0166-0934(01)00278-6 DO - 10.1016/S0166-0934(01)00278-6 ID - Myung2001 ER - TY - JOUR AU - Prabhu, R. AU - Joshi, V. AU - Garry, R. F. AU - Bastian, F. AU - Haque, S. AU - Regenstein, F. AU - Thung, S. N. AU - Dash, S. PY - 2004 DA - 2004// TI - Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone JO - Exp Mol Pathol VL - 76 UR - https://doi.org/10.1016/j.yexmp.2004.01.004 DO - 10.1016/j.yexmp.2004.01.004 ID - Prabhu2004 ER - TY - JOUR AU - Yin, Q. AU - Flemington, E. K. PY - 2006 DA - 2006// TI - SIRNAs against the Epstein barr virus latency replication factor, EBNA1, inhibit its function and growth of EBV-dependent tumor cells JO - Virology VL - 346 UR - https://doi.org/10.1016/j.virol.2005.11.021 DO - 10.1016/j.virol.2005.11.021 ID - Yin2006 ER - TY - JOUR AU - Inchauspe, G. AU - Zebedee, S. AU - Lee, D. H. AU - Sugitani, M. AU - Nasoff, M. AU - Prince, A. M. PY - 1991 DA - 1991// TI - Genomic structure of human prototype strain H of hepatitis C virus: comparison with American and Japanease isolates JO - Proc Natl Acad Sci (USA) VL - 88 UR - https://doi.org/10.1073/pnas.88.22.10292 DO - 10.1073/pnas.88.22.10292 ID - Inchauspe1991 ER - TY - JOUR AU - Brown, E. A. AU - Zhang, H. AU - Ping, L. H. AU - Lemon, S. M. PY - 1992 DA - 1992// TI - Secondary structure of the 5' non translated regions of hepatitis C virus and pestivirus genomic RNAs JO - Nucl Acids Res VL - 20 UR - https://doi.org/10.1093/nar/20.19.5041 DO - 10.1093/nar/20.19.5041 ID - Brown1992 ER - TY - JOUR AU - Honda, M. AU - Brown, E. A. AU - Lemon, S. M. PY - 1996 DA - 1996// TI - Stability of a stem-loop involving the initiator AUG controls the efficiency of internal initiation of translation of hepatitis C virus JO - RNA VL - 10 ID - Honda1996 ER - TY - JOUR AU - Kamoshita, N. AU - Tsukiyama-Kohara, K. AU - Kohara, M. AU - Nomoto, A. PY - 1997 DA - 1997// TI - Genetic analysis of internal ribosome entry site on hepatitis C virus RNA: implication for involvement of the highly ordered structure and cell type-specific transacting factors JO - Virology VL - 233 UR - https://doi.org/10.1006/viro.1997.8600 DO - 10.1006/viro.1997.8600 ID - Kamoshita1997 ER -