Figure 2From: Effect of ethanol on innate antiviral pathways and HCV replication in human liver cellsEthanol activates p38 MAPK in human liver cell cultures. Huh7 cells or primary human fetal hepatocytes (HFH) were left as untreated controls (C) or were treated with anisomycin (A) as a positive control, or with 25, 50, or 100 mM ethanol for 30 minutes. Active p38 MAPK was immunoprecipitated from cell lysates and kinase activity measured by phosphorylation of ATF-2. The figure is representative of 2 experiments that produced similar results.Back to article page