Mutant | Mutation | Expression | Binding | ASA |
---|---|---|---|---|
1 | E327 | 98 | 83 | 123 |
2 | K333 | 86 | 90 | 176 |
3* | K344 | 95 | 102 | 159 |
4 | K390 | 104 | 1 | 44 |
5 | D392 | 110 | 95 | 69 |
6 | D393 | 30 | 100 | 10 |
7 | K411 | 90 | 103 | 33 |
8 | D414 | 120 | 130 | 113 |
9 | D415 | 90 | 102 | 97 |
10* | R426 | 73 | 7 | 95 |
11 | N427 | 100 | 111 | 121 |
12 | D429 | 103 | 0 | 9 |
13 | T431 | 131 | 64 | 59 |
14 | K439 | 85 | 87 | 65 |
15 | R441 | 10 | 15 | 3 |
16* | Y442 | 105 | 110 | 68 |
17* | R444 | 80 | 86 | 52 |
18 | H445 | 124 | 103 | 113 |
19 | K447 | 87 | 85 | 138 |
20 | R449 | 96 | 101 | 178 |
21 | F451 | 69 | 71 | 64 |
22 | D454 | 50 | 4 | 25 |
23 | I455 | 77 | 6 | 89 |
24 | D463 | 87 | 81 | 70 |
25* | L472 | 95 | 99 | 172 |
26 | N473 | 100 | 0 | 70 |
27 | W476 | 80 | 76 | 126 |
28 | F483 | 91 | 3 | 2 |
29 | Q492 | 95 | 3 | 5 |
30 | Y494 | 50 | 7 | 21 |
31 | R495 | 97 | 19 | 7 |
32 | E502 | 110 | 84 | 175 |
33 | S17–276 | 90 | 0 | |
34 | S319–518 | 100 | 100 |