|  |  | Nucleotide | Amino acid | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Virus ID No. | Region | No of Clones | No of change/total | Mutation frequencya (10-3) | A→G or U→Cb (%) | Mean p-distancec(10-3) | Range (10-3) | No of change/total | Mutation frequencya(10-3) | Mean p-distancec(10-3) | Range (10-3) |
1F | C/PrM | 23 | 24/17733 | 1.4 | 66.7 | 2.67 | 0–6.7 | 13/5175 | 2.5 | 5 | 0–8.9 |
1H | C/PrM | 29 | 29/22359 | 1.3 | 69 | 2.45 | 0–6.7 | 17/6525 | 2.6 | 5.12 | 0–22.2 |
2H | C/PrM | 21 | 16/16191 | 1.0 | 81.3 | 2.03 | 0–6.7 | 9/4725 | 1.9 | 3.81 | 0–13.3 |
2F | C/PrM | 22 | 18/16962 | 1.1 | 72.2 | 2.17 | 0–6.7 | 10/4950 | 2.0 | 4 | 0–13.3 |
3H | C/PrM | 13 | 11/10023 | 1.1 | 72.7 | 1.81 | 0–4 | 7/2925 | 2.4 | 4.7 | 0–17.8 |
3F | C/PrM | 24 | 24/18504 | 1.3 | 75 | 2.55 | 0–8 | 13/5400 | 2.4 | 4.8 | 0–17.8 |
Mean ± std | C/PrM | 22 |  | 1.2 ± 0.15 | 72.8 ± 5.1 | 2.28 ± 0.3 |  |  | 2.3 ± 0.3 | 4.6 ± 0.5 |  |
1F | E/NS1 | 26 | 40/32240 | 1.2 | 72.5 | 2.23 | 0–6.5 | 21/10192 | 2.1 | 4.3 | 0–10.2 |
1H | E/NS1 | 13 | 47/16250 | 2.9 | 61.7 | 3.82 | 0–6.4 | 17/5096 | 3.3 | 6.6 | 0–7.6 |
2H | E/NS1 | 25 | 33/16250 | 2.0 | 93.9 | 3.88 | 0–5.6 | 34/9800 | 3.5 | 6.4 | 0–12.6 |
2F | E/NS1 | 13 | 15/22103 | 0.7 | 66.7 | 3.18 | 0–2.8 | 4/5096 | 0.8 | 7.6 | 0–9 |
3H | E/NS1 | 23 | 44/20240 | 2.2 | 72.7 | 3.83 | 0–4.8 | 55/9016 | 6.1 | 6.2 | 0–12.6 |
3F | E/NS1 | 20 | 39/24960 | 1.6 | 74.4 | 2.56 | 0–6.8 | 20/7840 | 2.6 | 4.8 | 0–21.7 |
Mean ± std | E/NS1 | 20 |  | 1.8 ± 0.8 | 73.7 ± 11 | 3.7 ± 0.7 |  |  | 3.1 ± 1.8 | 6 ± 1.2 |  |
1F | NS3 | 19 | 5/17005 | 0.3 | 60 | 0.9 | 0–3.5 | 8/4978 | 1.6 | 3.3 | 0–11.4 |
1H | NS3 | 27 | 16/24165 | 0.7 | 56.3 | 1.2 | 0–4.6 | 11/7074 | 1.6 | 3.1 | 0–11.4 |
2H | NS3 | 26 | 9/23270 | 0.4 | 33.3 | 1.2 | 0–4.6 | 6/6812 | 0.9 | 3.2 | 0–11.5 |
2F | NS3 | 25 | 16/22375 | 0.7 | 40 | 2.4 | 0–5.8 | 12/6550 | 1.8 | 5.7 | 0–15.3 |
3H | NS3 | 23 | 25/20585 | 1.2 | 16 | 1.6 | 0–4.6 | 6/6026 | 1.0 | 2.0 | 0–11.4 |
3F | NS3 | 18 | 8/16110 | 0.5 | 62.5 | 1.0 | 0–4.6 | 4/4716 | 0.8 | 1.6 | 0–11.4 |
Mean ± std |  | 23 |  | 0.6 ± 0.3 | 44.7 ± 18 | 1.4 ± 0.6 |  |  | 1.3 ± 0.4 | 3 ± 1.4 |  |
1F | NS5 | 13 | 29/23335 | 1.2 | 69 | 1.7 | 0–4.5 | 17/7748 | 2.2 | 4.1 | 0–8.4 |
1H | NS5 | 17 | 32/30515 | 1.0 | 71.9 | 2.4 | 0–5.6 | 31/10132 | 3.1 | 3.5 | 0–8.4 |
2H | NS5 | 18 | 51/32310 | 1.6 | 64.7 | 3.0 | 0–8.9 | 33/10728 | 3.1 | 6.1 | 0–18.5 |
2F | NS5 | 25 | 60/44875 | 1.3 | 65 | 2.5 | 0–5.6 | 47/14900 | 3.2 | 3.6 | 0–8.4 |
3H | NS5 | 16 | 64/28720 | 2.2 | 56.3 | 4.3 | 0–7.3 | 46/9536 | 4.8 | 6.8 | 0–15.2 |
3F | NS5 | 26 | 69/46670 | 1.5 | 52.2 | 3.7 | 0–6.7 | 52/15496 | 3.4 | 6.5 | 0–11.8 |
Mean ± std |  | 19 |  | 1.5 ± 0.4 | 63.2 ± 7.5 | 3.1 ± 0.9 |  |  | 3.3 ± 0.8 | 5.1 ± 1.5 |  |