Figure 8From: Replicative homeostasis II: Influence of polymerase fidelity on RNA virus quasispecies biology: Implications for immune recognition, viral autoimmunity and other "virus receptor" diseasesCell receptor (R) and normal ligand (L; insulin, PTH, leptin etc.) relationship (1; unbound, 2; activated), receptor permissive for virus cell entry (3) or blocked by polymorphism (Rp, 4). Receptor blockade by variant viral envelope proteins (green E, 5), blockade by antigenic envelope proteins stimulating "autoimmune"response apparently directed against self receptors (E, 6), competitive displacement of antigenic proteins by drug (D, e.g. statin, aspirin) abrogating immune response (7).Back to article page