Figure 7
From: Evidence that spontaneous reactivation of herpes virus does not occur in mice
Immunohistochemical staining for viral antigens. (a) Immunohistochemical staining of a tissue section through the ear graft site of a BALB/c scid mouse containing a ganglion from an acutely infected donor 7 days after grafting. In this immunoperoxidase-stained section, cells expressing HSV-1 antigens can be seen in the ganglion graft (arrows). (original magnification, 400×) (b) Immunohistochemical staining for HSV-1 antigens in the ganglion graft in a BALB/c scid mouse from the Reactivation Protocol. Cells expressing HSV-1 antigen are seen in both the graft and the surrounding ear cells at the graft site (arrows). (original magnification, 400×) (c) Immunohistochemical staining of a latent ganglion graft in a BALB/c scid recipient at 28 days after grafting. No evidence of cells expressing HSV-1antigens was seen in these tissue sections. (original magnification, 400×)