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Table 1 Clinical profile and clotting factor concentrate exposure of HIV-Exposed/HIVseronegative hemophiliacs.

From: Evidence of HIV exposure and transient seroreactivity in archived HIV-negative severe hemophiliac sera

   Hemophilia   Factor_concentrate exposure (1980–1985)
Patient # Year of birth Type Severity* Presence of inhibitor** Type Average Units/year
1 1972 B <1% No PCC 55,000
2 1956 B 4% No PCC <10,000
3 1966 A <1% Yes PCC 27,000
4 1953 A <1% No VIII 15,000
5 1977 B <1% No PCC 29,000
6 1971 A <1% Yes PCC 30,000
7 1931 A <1% No VIII 11,000
8 1976 B <1% No PCC 18,000
9 1964 B <1% No PCC 24,000
10 1976 A <1% Yes PCC 12,000
11 1957 A <1% No VIII 29,000
12 1950 A <1% Yes PCC 80,000
13 1969 B 2% No PCC 22,000
14 1959 A <1% No VIII 10,000
15 1946 B <1% No PCC 19,000
  1. * Normal factor VIII and Ix levels are 50–150%
  2. ** Inhibitor indicates the presence of a circulating antibody against the deficient factor; for patients with hemophilia A, an inhibitor often necessitates the use of PCC instead of factor VIII concentrates to control bleeding.