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Table 3 Characterisation of samples with biopsies considered moderate and severe and patients who died from HCC.

From: HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers

Sex/Group Patient ident Sample Id/Time of sample collection after onset or study initiation Age at time of sample collection Patient age at time of biopsy collection Knodell Index K130M/V131I HBeAg/Anti-HBe TSGO/TSGP
M/B 950-08 865M/2 y 4    -/- +/- 50/32
   6217M/12 y 14 15 2+1 = 3 +/+ -/-  
M/B 671-10 445E/19 d 8    -/- +/- 74/83
   5252M/9Y 17 18 2+2 = 4 +/+ -/+ 32/18
M/C 266-03 3751M/8 m 35    -/- -/+ 32/13
   6400M/6 y 40 40 3+3 = 6 +/+ -/- 36/13
M/B 496-04 6461E/2 y 12    -/+ -/- 45/40
   4904M/7 y 17 19 2+1 = 3 +/+ -/+ 28/25
M/B 969-04 467H/23 d 24    deletion -/- 500/550
   6604M/7 y 31 32 HCC 5+2 = 7 +/+ -/- ND/18
M/C 1232-06 1481M/10 m 12    -/+ -/+ 36/21
   6290M/9 y 22 23 2+1= 3 -/- -/+  
M/C 65-35 6891M/11 y     +/+ -/+ 55/50
    20 20 3+0 = 3    
M/C 158-01 6151M/11 y     +/+ -/+ 36/16
    33 35 1+2 = 3    
M/C 921-07 6403M/10 y     +/+ -/- 28/21
    31 32 3+1 = 4    
M/C 673-04 6572M/8 y     -/- -/- ND/9
    25 26 3+1 = 4    
M/C 5-02 6067M/9 y    2+2 = 4 -/- -/+ 32/16
    53 54     
M/C 671-06 6593M/15 y     -/- -/- ND/13
    26 26 4+3 = 7    
M/C 671-09 5251M/9y    2+4 = 6 -/- -/+ 28/18
    16 19     
M/B 1688-16 3254H/3 d 3   HCC -/- -/- 475/225
  16 6653M/3 y 6   NB +/+ -/- ND/36
M/B 1400-01 575H/2 d 65   HCC -/- -/- 610/1200
   5433M/4 Y 69   T -/- +/- 55/55
   6825H/7 y 72    -/- +/- ND/55
M/C 1205-15 5399M/7 y 35   HCC -/- -/+ 32/28
  1. ND = Not done, HCC = Hepatocellular carcinoma, T = tumor tissue only.