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Table 3 Characterisation of samples with biopsies considered moderate and severe and patients who died from HCC.

From: HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers

Sex/Group

Patient ident

Sample Id/Time of sample collection after onset or study initiation

Age at time of sample collection

Patient age at time of biopsy collection

Knodell Index

K130M/V131I

HBeAg/Anti-HBe

TSGO/TSGP

M/B

950-08

865M/2 y

4

  

-/-

+/-

50/32

  

6217M/12 y

14

15

2+1 = 3

+/+

-/-

 

M/B

671-10

445E/19 d

8

  

-/-

+/-

74/83

  

5252M/9Y

17

18

2+2 = 4

+/+

-/+

32/18

M/C

266-03

3751M/8 m

35

  

-/-

-/+

32/13

  

6400M/6 y

40

40

3+3 = 6

+/+

-/-

36/13

M/B

496-04

6461E/2 y

12

  

-/+

-/-

45/40

  

4904M/7 y

17

19

2+1 = 3

+/+

-/+

28/25

M/B

969-04

467H/23 d

24

  

deletion

-/-

500/550

  

6604M/7 y

31

32

HCC 5+2 = 7

+/+

-/-

ND/18

M/C

1232-06

1481M/10 m

12

  

-/+

-/+

36/21

  

6290M/9 y

22

23

2+1= 3

-/-

-/+

 

M/C

65-35

6891M/11 y

   

+/+

-/+

55/50

   

20

20

3+0 = 3

   

M/C

158-01

6151M/11 y

   

+/+

-/+

36/16

   

33

35

1+2 = 3

   

M/C

921-07

6403M/10 y

   

+/+

-/-

28/21

   

31

32

3+1 = 4

   

M/C

673-04

6572M/8 y

   

-/-

-/-

ND/9

   

25

26

3+1 = 4

   

M/C

5-02

6067M/9 y

  

2+2 = 4

-/-

-/+

32/16

   

53

54

    

M/C

671-06

6593M/15 y

   

-/-

-/-

ND/13

   

26

26

4+3 = 7

   

M/C

671-09

5251M/9y

  

2+4 = 6

-/-

-/+

28/18

   

16

19

    

M/B

1688-16

3254H/3 d

3

 

HCC

-/-

-/-

475/225

 

16

6653M/3 y

6

 

NB

+/+

-/-

ND/36

M/B

1400-01

575H/2 d

65

 

HCC

-/-

-/-

610/1200

  

5433M/4 Y

69

 

T

-/-

+/-

55/55

  

6825H/7 y

72

  

-/-

+/-

ND/55

M/C

1205-15

5399M/7 y

35

 

HCC

-/-

-/+

32/28

  1. ND = Not done, HCC = Hepatocellular carcinoma, T = tumor tissue only.