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Table 1 Duration of survival of HSV-1 infected scid mice.

From: Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1

  

Treatmenta

Expt.

Virus

PBS

rabbit IgG

NK-depletedb

WBC-depletedc

1 d

KOS

15.8 ± 0.8 (n = 9) f

34.9 ± 2.8 (n = 9)

23.5 ± 0.9 (n = 9)

ND g

2

KOS-GFP

19.0 ± 0.9 (n = 5)

36.8 ± 3.8 (n = 5)

35.0 ± 0.6 (n = 5)

ND

3 e

KOS

18.1 ± 0.8 (n = 8)

ND

ND

12.1 ± 0.7 (n = 8)

4

KOS-GFP

23.7 ± 1.8 (n = 6)

ND

ND

14.0 ± 0.6 (n = 5)

Summary

19.2 ± 1.7 (n = 28)

35.9 ± 1.3 (n = 14)

29.3 ± 5.8 (n = 14)

13.1 ± 0.9 (n = 15)

  1. a BALB/c scid mice were treated with PBS, control rabbit IgG, rabbit anti-asialo GM1, or cyclophosphamide (CyP) as described in Materials and Methods.
  2. b BALB/c scid mice were treated with rabbit anti-asialo GM1.
  3. c BALB/c scid mice were treated with cyclophosphamide.
  4. d The results of Experiment 1 are presented in Figure 4.
  5. e The results of Experiment 3 are presented in Figure 5.
  6. f Mean ± SEM days of survival after ocular HSV-1 inoculation of scid mice (n= number of mice per treatment).
  7. g Not determined in this experiment.
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Virology Journal

ISSN: 1743-422X