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Table 1 Duration of survival of HSV-1 infected scid mice.

From: Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1

   Treatmenta
Expt. Virus PBS rabbit IgG NK-depletedb WBC-depletedc
1 d KOS 15.8 ± 0.8 (n = 9) f 34.9 ± 2.8 (n = 9) 23.5 ± 0.9 (n = 9) ND g
2 KOS-GFP 19.0 ± 0.9 (n = 5) 36.8 ± 3.8 (n = 5) 35.0 ± 0.6 (n = 5) ND
3 e KOS 18.1 ± 0.8 (n = 8) ND ND 12.1 ± 0.7 (n = 8)
4 KOS-GFP 23.7 ± 1.8 (n = 6) ND ND 14.0 ± 0.6 (n = 5)
Summary 19.2 ± 1.7 (n = 28) 35.9 ± 1.3 (n = 14) 29.3 ± 5.8 (n = 14) 13.1 ± 0.9 (n = 15)
  1. a BALB/c scid mice were treated with PBS, control rabbit IgG, rabbit anti-asialo GM1, or cyclophosphamide (CyP) as described in Materials and Methods.
  2. b BALB/c scid mice were treated with rabbit anti-asialo GM1.
  3. c BALB/c scid mice were treated with cyclophosphamide.
  4. d The results of Experiment 1 are presented in Figure 4.
  5. e The results of Experiment 3 are presented in Figure 5.
  6. f Mean ± SEM days of survival after ocular HSV-1 inoculation of scid mice (n= number of mice per treatment).
  7. g Not determined in this experiment.