Skip to main content
Figure 1 | Virology Journal

Figure 1

From: Human cytomegalovirus uracil DNA glycosylase associates with ppUL44 and accelerates the accumulation of viral DNA

Figure 1

Recombinant viruses. The top line represents the CMV genome with the region surrounding UL114 expanded below. The second line represents the structure of the region in the parent virus (AD169). The third line labeled "RC2620" depicts the 1.2 kb insertion containing the E. coli gpt gene (white arrow) that replaces most of the UL114 ORF. The final three lines represent the same region in Towne and depict the placement of the 35 aa ICP4 epitope tags in the ORF. The entire ORF was also deleted in Towne as a control and resulted in the same slow replication phenotype as was observed in the AD169 strain.

Back to article page

Virology Journal

ISSN: 1743-422X