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Table 1 Initial peptides synthesized and tested for inhibitory activity.

From: Peptide inhibitors of dengue virus and West Nile virus infectivity

Peptide

Sequence

Locationa

Concentration (μM)

% Inhibition +/- SD

DN80

MVDRGWGNHAGLFGKGSIV

386–400

49.9

17 +/- 10

DN57

AWLVHTQWFLDLPLPWLPGADTQGSNWI

485–503

30.6

7 +/- 4

DN81

AWLVHRQWFLDLPLPWLPG

485–512

42.6

25 +/- 8

DN59

MAILGDTAWDFGSLGGVFTSIGKALHQVFGAIY

692–724

29.0

93 +/- 2

WN82

VVDRGWGNGAGLFGKGSID

396–410

52.5

4 +/- 13

WN53

TFLVHREWFMDLNLPWSSAGSTVWR

500–518

98.7

56 +/- 5

WN83

TFLVHREWFMDLNLPWSSA

500–524

128.0

70 +/- 2

  1. a numbering from the beginning of the E polyprotein in either DENV or WNV.