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Table 5 Predicted amino acid residue at the indicated location in the TM region of Env. Bold indicates unique amino acids in clones 129 and 169.

From: Development and characterization of positively selected brain-adapted SIV

Env – gp41

573

631

676

713

734

737

741

751

752

760

764

767

785

802

821

850

855

SIVmac239

K

K

D

M

Q

I

P

R

D

S

W

E

S

L

T

G

T

SIVmac316

T

K

D

V

Q

I

P

G

D

S

W

Stop

-

-

-

-

-

SIV17E-Cl

K

K

N

V

Q

*

*

*

*

*

*

*

*

*

*

*

*

SIV17E/Fr

K

K

D

M

Q

I

P

G

D

S

Stop

-

-

-

-

-

-

SIVmac251

K

N

D

M

Q

I

P

G

D

S

W

E

S

L

T

G

T

SIVmac32H

K

D

D

M

Q

I

P

G

D

S

W

E

S

L

T

G

T

SIVmac1A11

K

K

D

M

Stop

-

-

-

-

-

-

-

-

-

-

-

-

Clone 129

K

D

D

M

Q

T

Q

G

D

R

W

E

N

F

A

R

T

Clone 169

K

D

D

M

Q

T

Q

G

G

R

W

E

N

F

A

R

A

  1. *sequence not available, – no amino acid residue.