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Table 2 In vitro syncytia formation and viral antigen production. The molecular clones, derived from microglia of the indicated monkey, were tested by transfection and subsequent growth in 174xCEM cells.

From: Development and characterization of positively selected brain-adapted SIV

Clone Monkey Longest time to Syncytia Formation Longest time to Detectable p27
Group 1    
109 225 7 days 7 days
129 225 7 days 7 days
141 225 7 days 7 days
142 225 7 days 7 days
169 321 7 days 7 days
Group 2    
108 225 12 days 12 days
122 225 12 days 12 days
144 225 12 days 12 days
146 225 15 days 18 days
153 321 9 days 10 days
159 321 12 days 12 days
Group 3    
104 225 18 days 14 days
115 225 18 days 14 days
116 225 18 days 18 days
134 225 18 days 18 days
143 225 Never 18 days
164 321 12 days 12 days
171 321 Never 15 days
173 321 Never 15 days
Control    
SIVmac239   4 days 7 days