Figure 5
From: Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range
Predicted structures of the mesonivirus ORF1a/ORF1b ribosomal frame-shift element (RFS) element. (A). Stem-loop structure predicted previously for NDiV [3] using pseudoknotsRG software, illustrating nucleotides that are substituted in various viruses (red circles). Nucleotide substitutions (which are primarily non-compensatory) are shown in the boxes. The corresponding sequence alignment is shown in Additional file 4: Figure S4. (B). An alternative conserved pseudoknot structure predicted from the multiple sequence alignment using ipknot software. The putative ‘slippery’ sequence (GGAUUUU) at the ribosomal frame-shift site is shaded in grey.