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Figure 3 | Virology Journal

Figure 3

From: Inhibition of hepatitis C virus by an M1GS ribozyme derived from the catalytic RNA subunit of Escherichia coli RNase P

Figure 3

Schematic structure of the DNA sequences encoding M1GS ribozymes used in this study. (A) M1GS ribozyme with its guide sequence (GS) directly linked to the 3′ terminus of M1 RNA. (B) M1GS ribozyme containing a bridge sequence, which is of 88 nt-length and links a GS to the 3′ terminus of M1 RNA. (C) Cholesterol-modified M1GS ribozyme containing a cholesterol molecule to the 5′ terminus of M1 RNA, with a bridge sequence between GS and M1 RNA.

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