From: Diagnosis of genital herpes simplex virus infection in the clinical laboratory
HSV-1 | HSV-2 | ||||||
---|---|---|---|---|---|---|---|
Assay | Manufacturer | Format | Collection method | Sensitivity | Specificity | Sensitivity | Specificity |
Biokit HSV-2 Rapid Test | Biokit | Point of care | Heparinized capillary whole blood, serum | NA | NA | 93%-96% | 95%-98% |
HerpeSelect HSV-1 and HSV-2 Immunoblot | Focus Diagnostics | Western blot with recombinant proteins | Serum | 99.3% | 95.1% | 97.3% | 93.7% |
HerpeSelect HSV-1 ELISA, HerpeSelect HSV-2 ELISA | Focus Diagnostics | ELISA | Serum | 91.2%-96% | 92. 3%-95.2% | 96.1% -100% | 97.0%-96.1% |
CaptiaHsv 1 IgG Type Specific Elisa Kit&CaptiaHsv 2 IgG Type Specific Elisa Kit | Trinity Biotech | ELISA | Serum | 87.9%-87.7% | 100%-98.2% | 96.7%-100% | 90.3%-91.5% |
Liaison HSV-1 & Liaison HSV-2 Type SpecificIgGAssay | Diasorin | ELISA | Serum | 96.9%-98.7% | 91.3%-96.8% | 98.1%-94.8% | 98.0%-97.3% |
Zeus ELISA HSV GG-2 IgG Test System & Zeus ELISA HSV GG-1 IgG Test System | Zeus Scientific | ELISA | Serum | 96.8% | 97.1% | 98.8% | 100% |
BioPlex HSV-1 & HSV-2 IgG panel | Biorad | Luminex | Serum, lithium heparini plasma, EDTA plasma | 100%-100% | 98. 3%-97.4% | 99.4%-100% | 100%-100% |
Elecsys HSV-1 IgG and HSV-2 IgG assays | Roche Diagnostics | Chemiluminescence | Serum, lithium heparin plasma, EDTA plasma | 94.2%-91.0% | 90. 3%-95.7% | 93.6%-97.8% | 98.7%-98.7% |