Figure 3From: Oral immunization with recombinant enterovirus 71 VP1 formulated with chitosan protects mice against lethal challengeDetection of EV71 specific mucosal IgA antibody. Secretions of vaginal, intestinal, respiratory tract and fresh fecal pellets were collected on day 42 and immediately frozen at −80°C. Titers of specific IgA antibody in: (A) Intestine (diluted at 1:10); (B) Stool homogenates (diluted at 1:4); (C) Respiratory tract (diluted at 1:2); (D) Vaginal secretions (diluted at 1:2) were detected by indirect ELISA. Data were expressed as mean OD.450 value ± SD. (* P < 0.05, ** P < 0.01).Back to article page