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Figure 1 | Virology Journal

Figure 1

From: Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus challenge in SCID mice

Figure 1

Serological characterization of pre-pandemic IVIG (open bars) and post-pandemic H-IVIG (hatched bars). Antibody titers against the seasonal H1N1 strain A/New Caledonia/20/1999 (sH1N1) (white bars) and pandemic A/California/07/2009 (pH1N1) (grey bars) were determined by hemagglutination inhibition (HI), microneutralization (MN) and enzyme-linked lectin assay (ELLA, reported as NA inhibition [NAi]), respectively. Results are given as geometric mean titer (GMT) ± 95% confidence interval (CI). Statistical differences were calculated by unpaired Student t-test analysis (GraphPad Prism software). *** P < 0.0001. GMTs were calculated by testing 13 individual lots of IVIG and 2 lots of H-IVIG.

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Virology Journal

ISSN: 1743-422X