Figure 4From: Complete genome sequence and pathogenesis of bovine viral diarrhea virus JL-1 isolate from cattle in ChinaThe pathology detection following inoculated with BVDV JL-1. Histopathology appearances of H&E-stain (A and B), A. spleen, showing the significantly wided periarterial lymphatic sheath and lymphocytes depletion in red pulp (100×); B. intestines: showing hemorrhage and shedding in the small intestine villi (100×). Immunohistochemistry (IHC) detection of BVDV antigen (C and D). C. spleen, virus antigens in mononuclear cells randomly scattered in splenic red pulp (200×); D. virus antigens in epithelium of intestines (200×).Back to article page