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Figure 2 | Virology Journal

Figure 2

From: Recombination and pseudorecombination driving the evolution of the begomoviruses Tomato severe rugose virus (ToSRV) and Tomato rugose mosaic virus (ToRMV): two recombinant DNA-A components sharing the same DNA-B

Figure 2

Alignment of the common regions and the Rep proteins of ToSRV-[BR:PG1:Pep:03] and ToRMV-[BR:Ub1:96]. A. Common region alignment. The TATA box, G-box and the conserved nonanucleotide are indicated in light gray. Iterated direct and inverted repeats (iterons) are boxed. The arrows indicate the direction of the repeats. Asterisks indicate nucleotide positions which are conserved among all four aligned sequences. Arrowheads indicate differences in nucleotide sequence among the four CRs. B. Rep protein alignment. Dark gray boxes correspond to the domain associated with sequence-specific recognition of iterons (iteron-related domain, IRD), motif 1, motif 2 and specificity determinants (SPDs), which according to [15] and [37] are conserved in rolling-circle replication-initiator proteins, including geminivirus Rep proteins.

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