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Table 1 The demographic and clinical characteristics of subjects

From: Expansion of circulating TFH cells and their associated molecules: involvement in the immune landscape in patients with chronic HBV infection

Parameters

HC

CHB (HBeAg+)

IT

IC

CHB (HBeAg-)

Number

25

14

8

10

6

Age (years)

     

Mean ± SD

30.6 ± 10.6

27.9 ± 12.0

26.8 ± 6.7

46.1 ± 14.8

42.8 ± 12.2

Sex N (%)

     

Male

12(48.0)

5(35.7)

5(62.5)

5(50.0)

2(33.3)

Female

13(52.0)

9(64.3)

3(37.5)

5(50.0)

4(66.7)

HBV-DNA (log10 copies/mL)

Mean ± SD

NA

6.5 ± 0.4

7.2 ± 0.8

2.0 ± 1.3

4.6 ± 0.2

ALT (U/L)

     

Mean ± SD

≤40

504.1 ± 635.3

26.1 ± 8.4

21.7 ± 9.9

118.5 ± 56.7

AST (U/L)

     

Mean ± SD

≤40

430.3 ± 657.6

23.6 ± 6.5

27.8 ± 9.3

58.3 ± 21.4

HBeAg/Anti-HBe

0/0

14/0

8/0

0/10

0/6

  1. NA, not applicable; HC, healthy control; CHB(HBeAg+), HBeAg-positive chronic hepatitis B; IT, immune tolerant carrier; IC, inactive carrier; CHB(HBeAg-), HBeAg-negative chronic hepatitis B.