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Figure 1 | Virology Journal

Figure 1

From: Expansion of circulating TFH cells and their associated molecules: involvement in the immune landscape in patients with chronic HBV infection

Figure 1

Fluorescence-activated cell sorter (FACS) analysis of the frequency of peripheral blood CXCR5+CD4+T cells in patients with chronic HBV infection patients. (A) Gating strategy. (B) The percentage of circulating CXCR5+CD4+ T cells was compared between the two groups. (C) The percentage of CXCR5+CD4+ T cells was significantly higher in patients with chronic HBV infection than in healthy controls (P < 0.05). (D) Comparison of the frequency of CXCR5+CD4+ T cells in the IT, IC, CHB(HBeAg+), CHB(HBeAg-) and HC groups. HC, healthy controls; HBV, patients with chronic HBV infection; IT, immune tolerant carrier; IC, inactive carrier; CHB1, HBeAg-negative chronic hepatitis B; CHB2, HBeAg-positive chronic hepatitis B; PI, propidium iodide. The horizontal lines represent the median values (±SEM).

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