The burden, distribution and risk factors for cervical oncogenic human papilloma virus infection in HIV positive Nigerian women

Table 5 Variables independently associated with hr HPV after controlling for confounders in a three model multivariate logistic analysis

Variables at enrolment	Initial model^a	2nd Model^b	Final model^c
Variables at enrolment	OR (95% CI)	OR (95% CI)	OR (95% CI)
HIV status (515)
Negative	1 (ref)	1 (ref)	1 (ref)
Positive	1.7 (1.3 -2.5)	1.7 (1.3-2.5)	1.8 (1.4-2.2)
Antiretroviral drug use (220)
Not on drugs	1 (ref)	1 (ref)	1 (ref)
On drugs	0.4 (0.3 - 0.9)	0.4 (0.3 - 0.9)	0.4 (0.3-0.5)
CD4 cell count (220)
<200	2.9 (1.3-7.1)	2.5 (1.5-6.1)	2.4 (1.7-5.9)
200 – 499	1 (ref)	1 (ref)	1 (ref)
500 and above	0.6 (0.3-1.0)	0.6 (0.5-0.9)	0.7 (0.5-0.8)
Viral load (220)
<1000	0.5 (0.2-1.9)	0.6 (0.4 -1.3)	0.6 (0.3 -1.4)
1000 – 10,000	1 (ref)	1 (ref)	1 (ref)
≥ 10,000	3.1 (1.1-9.9)	3.1 ( 0.9- 8.7)	2.7 (0.6- 8.1)

^aadjusted for age ^badjust for HIV status and antiretroviral drug use ^cin addition to a and c adjusted for type of community, life time sexual partner and marital status.

ISSN: 1743-422X