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Figure 2 | Virology Journal

Figure 2

From: Controlled release delivery of penciclovir via a silicone (MED-4750) polymer: kinetics of drug delivery and efficacy in preventing primary feline herpesvirus infection in culture

Figure 2

FHV-1 infection of CRFK cells and protection by PCV-containing silicone implants. CRFK cells were seeded and treated with nothing (“None”), PCV at 10 μg/mL in PBS (“Penciclovir”), a single 15-mm implant of MED-4750 silicone alone (“MED-4750”), or a single 15-mm implant of MED-4750 containing 33% PCV (“33% Penciclovir/MED-4750”). One day after treatment, FHV-1 (102 pfu/well) was added to cells shown in the bottom row (“FHV-1”) or cells were left uninfected (top row, “Mock”). Photos of these cultures were obtained four days after infection.

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