Figure 2
From: CRTC2 enhances HBV transcription and replication by inducing PGC1α expression
FSK robustly enhances CRTC2-induced HBV transcription and replication. (A) Luciferase activity in Huh-7 cells transfected with pGL-3-ENII-luc and p-CRTC2 in the presence or absence of FSK. (B-D) HBV core protein expression (B), HBV mRNA levels (C), and HBV DNA replication intermediates (D) in Huh-7 cells transfected with p-CRTC2 and 1.3× wtHBV plasmid, in the presence or absence of FSK. *p < 0.05; **p < 0.01.