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Table 4 G367R infectivity in cell cocultures

From: Identification of an env-defective HIV-1 mutant capable of spontaneous reversion to a wild-type phenotype in certain T-cell lines

Weeks G367R + VSV-G CPEa
  MT2b: 105 MT4: 105
2c 293 T SNd -e -
Co + -
TZM-bl SN - -
Co + -
4 293 T SN - -
Co + -
TZM-bl SN - -
Co + -
6 293 T SN - -
Co + -
TZM-bl SN - -
Co + -
10 293 T SN - -
Co + -
TZM-bl SN + +
Co + +
  1. 293 T or TZM-bl donor cells were infected by pseudotyped G367R viruses. The infected cells or supernatants were used to infect target cells at different time points.
  2. aCPE = cytopathic effect.
  3. btarget cell type and numbers used for infection.
  4. cnumber of weeks after infection of donor cells.
  5. dSN = supernatants of infected donor cells were used for infection, Co = coculturing target cells with infected cells at a ratio of 1:5.
  6. e−designates that CPE was not observed over 14 days. + designates that CPE was observed within 14 days.