Figure 4From: Development of kinomic analyses to identify dysregulated signaling pathways in cells expressing cytoplasmic PrPDifferential expression of protein kinases in N2a cells expressing different cytoplasmic PrP mutants. Multiplex Western blots of lysates from N2a cells transfected with empty vector (vector), or vector encoding CyPrPEGFP (CyPrP), CyPrPEGFP124stop (124stop), or CyPrPEGFP124-230 (124–230). Molecular weights in kDa are indicated on the right. The protein kinases p70S6K (set 1) and PKACβ (set 2) are indicated by white arrowheads and enlarged, to illustrate their differential expression in cells expressing the different mutants.Back to article page