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Table 3 Linear regression of HBZ binding alleles to PVL

From: HTLV-1 proviral integration sites differ between asymptomatic carriers and patients with HAM/TSP

Outcome

Predictor

Cohort*

n

Slope

p value

Controlling for:

Log PVL

# HBZ binding alleles

Kagoshima HAM, AC

HAM: 221 AC: 200

-0.12

0.021

Age, sex, disease status

Log PVL

# HBZ binding alleles

Kumamoto AC

AC: 98

-0.12

0.28

 

Log PVL

# HBZ binding alleles

Kagoshima HAM, AC & Kumamoto AC

HAM: 229 AC: 300

-0.13

0.0058

Disease status

  1. *Only individuals who had all the relevant information were included in the regression. Age, sex and disease status were included as factors where possible as they may vary with PVL.
  2. Age and sex information was not available for the Kumamoto AC cohort.
  3. PVL: proviral load, AC: Asymptomatic carrier, #: number of.