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Table 3 Conserved and variable regions of HCV in the amino acid sequences of core, NS5B among the two groups

From: Occurrence of genetic modifications in core, 5′UTR and NS5b of HCV associated with viral response to treatment

Treatment groups Conserved amino acids positions P value Variable amino aqcids positions P value
  Core NS5B   Core NS5B  
Group 1 (n = 75) 3, 9, 10, 15, 21, 23, 25, 28, 35, 105, 106, 123, 134, 136, 137, 142 14,18,65,120,133,141 < 0.001 24, 29, 34, 36, 38, 39, 41, 65, 72, 85, 112,141, 151 35, 43, 44,47, 48, 51, 59, 62, 65, 68, 70, 87, 89, 95, 102, 107, 112, 118, 120, 129, 221, 240, 256 0.002
Group 2(n = 75) 3, 7, 9, 25, 28, 35, 106, 165, 205 13, 18, 24, 67, 85, 109, 120, 134, 143, 154, 153 < 0.001 23, 29, 35, 37, 38, 41, 43, 54, 56, 67, 72, 78, 85, 105, 112, 120, 135, 141, 156 26, 35, 48, 95, 105, 109, 108, 114, 118, 132, 143, 154, 165, 163, 172, 187, 201, 221, 240, 289, 267,256 < 0.03