Skip to main content
Figure 2 | Virology Journal

Figure 2

From: Emerging antiviral resistant strains of influenza A and the potential therapeutic targets within the viral ribonucleoprotein (vRNP) complex

Figure 2

Antiviral targets of nucleoprotein. Analysis of NP monomer crystal structure extracted from NP trimer crystal structure “2IQH” [39] using Deep View-Swiss-PdbViewer 4.0. Residue color determined by accessibility. Greatest to least accessible as follows: red, orange, yellow, green, light blue, and dark blue. Residue 289 is the proposed site of interaction with the antiviral compound nucleozin [41]. An intermolecular salt bridge formed by residues 339 and 416 of NP is essential for oligomerization and can be disrupted by small molecule inhibitors [42].

Back to article page

Virology Journal

ISSN: 1743-422X