Figure 4

Phylogenetic analysis of 72 Guangzhou CV-A6 isolates from 2010–2012 (■ 2010 isolates ● 2011 isolates ▲ 2012 isolates ○2011 severe cases ∆ 2012 severe cases) and 38 reference isolates from other Chinese and international locations based on partial VP1 nucleotide sequences. The dendrogram was generated by the neighbor-joining method (bootstrap analysis with 1,000 pseudo replicate data sets) by Mega 5.0. Genotypes are shown to the right of the tress and bootstrap values are shown at each major node. The scale at the bottom indicates a measurement of relative phylogenetic distance.