Table 2 Titers of RSV in the upper and lower respiratory tract of BALB/c mice
| Â | Lung | Nose | ||||
|---|---|---|---|---|---|---|
Immunogena | Virus | Days postinfectionb | Mean RSV titer ± SDdlog PFU ml−1 | Mice protectedc(%) | Mean RSV titer ± SDdlog PFU ml−1 | Mice protectedc(%) |
FI-RSV | RSV-Long | 3 | 4.56 ± 0.28 | 0 | 4.98 ± 0.38 | 0 |
5 | 5.11 ± 0.45 | 0 | 5.28 ± 0.55 | 0 | ||
7 | 4.78 ± 0.36 | 0 | 5.08 ± 0.25 | 0 | ||
10 | 4.96 ± 0.20 | 0 | 4.85 ± 0.48 | 0 | ||
21 | 3.38 ± 0.18 | 0 | 3.55 ± 0.33 | 0 | ||
rLong | RSV-Long | 3 | <2.68 | 100 | 2.58 ± 0.28 | 75 |
5 | <2.68 | 100 | 2.96 ± 0.20 | 75 | ||
7 | <2.68 | 100 | <1.98 | 100 | ||
10 | <2.68 | 100 | <1.98 | 100 | ||
21 | <2.68 | 100 | <1.98 | 100 | ||
rLong-∆G-EGFP | RSV-Long | 3 | <2.68 | 100 | 2.69 ± 0.24 | 75 |
5 | <2.68 | 100 | 3.17 ± 0.16 | 50 | ||
7 | <2.68 | 100 | 2.25 ± 0.21 | 75 | ||
10 | <2.68 | 100 | <1.98 | 100 | ||
21 | <2.68 | 100 | <1.98 | 100 | ||
Mock | RSV-Long | 7 | 4.18 ± 0.25 | 0 | 4.03 ± 0.20 | 0 |
Mock | Mock | 7 | <2.68 | 100 | <1.98 | 100 |