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Table 2 List of FMDV/O isolates used in the study

From: Characterization of monoclonal antibodies against foot-and-mouth disease virus serotype O and application in identification of antigenic variation in relation to vaccine strain selection

FMD/O Isolates

GenBank accession#

Topotypea

Antigenic ELISA rbvalue

VNT r1by NCFADc

VNT r1by WRLFMD (reported year)

Manisa

 

ME-SA

1.00

1.00

-d

AFG/41/11

KJ606977

ME-SA

0.69

0.13

< 0.3 (2011)

BHU/39/04

 

ME-SA

0.45

0.63

-

BUL/3/11

 

ME-SA

0.78

2.63

> 0.3 (2011)

IRAQ/5/94

 

ME-SA

0.70

0.52

-

IRN/11/06

KJ606980

ME-SA

0.41

0.21

-

IRN/31/10

 

ME-SA

0.68

0.39

-

IRN/8/05

 

ME-SA

0.39

0.63

-

KRG/1/06

 

ME-SA

-0.13

1.66

-

KRG/2/06

 

ME-SA

-0.28

2.34

-

KUW/1/11

KJ606981

ME-SA

0.71

0.16

<0.3 (2011)

EGY/8/06

 

ME-SA

0.81

0.66

-

NEP/3/10

 

ME-SA

0.47

1.17

> 0.3 (2011)

PAK/1/10

 

ME-SA

0.52

0.79

0.46 (2010)

SAU/1/09

 

ME-SA

0.68

0.79

0.74 (2009)

SAU/4/05

 

ME-SA

0.57

0.45

0.78 (2005)

SAU/7/08

 

ME-SA

0.61

0.85

-

UAE/2/03

 

ME-SA

0.76

0.87

-

UAE/2/10

 

ME-SA

0.57

1.32

0.39 (2010)

UAE/9/09

KJ606983

ME-SA

0.68

0.12

-

UKG/11/01

 

ME-SA

0.65

1.45

-

UKG/13708/01

 

ME-SA

0.75

1.32

-

UKG/14221/01

 

ME-SA

0.76

1.00

-

VIT/32/11

KJ606984

ME-SA

0.34

0.13

<0.3 (2011)

KEN/62/09

 

EA-1

0.66

0.39

-

ETH/39/09

KJ606978

EA-3

0.48

0.02

0.16 (2009)

NIG/15/09

 

EA-3

0.30

1.58

> 0.3 (2010)

SOM/1/07

 

EA-3

0.53

0.81

-

SUD/3/08

 

EA-3

0.55

0.79

-

TAN/5/09

 

EA-2

0.70

2.69

> 0.3 (2010)

ZAM/1/10

 

EA-2

0.64

1.00

-

BFS1860

 

Euro-SA

0.44

0.32

-

ECU/4/10

KC519630

Euro-SA

0.18

0.05

-

UKG/685/07

 

Euro-SA

0.74

2.00

-

HKN/1/10

 

SEA

0.58

0.63

0.5 (2010)

HKN/2/11

KJ606979

SEA

0.07

0.10

<0.3 (2011)

MAY/1/05

 

SEA

0.59

0.78

-

MYA/1/10

 

SEA

0.50

1.70

-

MYA/11/09

 

SEA

0.55

1.55

-

SKR/4/10

 

SEA

0.58

1.20

0.57 (2010)

VIT/7/06

 

SEA

0.66

0.81

-

SEN/8/06

 

WA

0.48

0.60

-

MAI/15/06

 

WA

0.44

1.05

-

TAW/10/97

 

CATHAY

0.73

0.35

-

TAW/12/98

KJ606982

CATHAY

0.76

0.19

-

VIT/9/05

 

CATHAY

0.69

0.50

-

  1. aMiddle East-South Asia (ME-SA); Southeast Asia (SEA); East Africa (EA); Europe-South America (Euro-SA); West Africa (WA).
  2. bCorrelation coefficient between O1Manisa and each isolate.
  3. cNational Centre for Foreign Animal Disease (NCFAD), Canada.
  4. dInformation is not available.
  5. The correlation coefficient (r) for the panel of mAb was calculated between O1/Manisa and each isolate in the antigenic ELISA and the r1 values was determined in 2D-VNT using an O/Manisa vaccinated serum.