Skip to main content
Figure 3 | Virology Journal

Figure 3

From: Characterization of monoclonal antibodies against foot-and-mouth disease virus serotype O and application in identification of antigenic variation in relation to vaccine strain selection

Figure 3

Alignment of partial capsid amino acid sequences of unmatched FMDV/O field isolates and reference strain O1/Manisa. The capsid proteins of VP1, VP2, and VP3 of the 9 FMDV isolates (shown in Table 3) were aligned by Clustal-W. Only the regions containing 5 previously determined antigenic sites and unique amino acid substitutions of unmatched isolates and reference strain are shown for clarity. The identical amino acid residues are indicated by dots. Amino acid deletions are indicated as hyphens. The single letter amino acid code is used. Previously identified antigenic sites for FMDV/O are indicated with solid horizontal lines or closed circles above the sequences. Amino acid residues with unique substitutions in the 9 sequences are indicated by open boxes, and the VP1 GH loop residues 130-160 is indicated by a dashed line shown above the sequences.

Back to article page