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Table 2 Clinical performance characteristics compared to the modified gold standard

From: Detection of circulating norovirus genotypes: hitting a moving target

Method Clinical Parameters*
Sensitivity (%) Specificity (%) Kappa False positivity rate (%)
Real-time RT-PCR 100.0 (91.5 – 100.0) 100.0 (98.2 – 100.0) 1.00 (0.90 – 1.00) 0.00
EP-JV 71.9 (58.6 – 71.9) 98.1 (95.3 – 99.5) 0.76 (0.58 – 0.84) 1.99
EP-SR 62.5 (48.4 – 71.7) 96.8 (93.8 – 98.7) 0.65 (0.46 – 0.77) 3.36
EP-JV and EP-SR 75.0 (60.3 – 85.5) 94.8 (91.7 – 97.0) 0.70 (0.52 – 0.82) 5.47
  1. *When applicable, 95% confidence intervals are indicated in parentheses.