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Table 2 Clinical performance characteristics compared to the modified gold standard

From: Detection of circulating norovirus genotypes: hitting a moving target

Method

Clinical Parameters*

Sensitivity (%)

Specificity (%)

Kappa

False positivity rate (%)

Real-time RT-PCR

100.0 (91.5 – 100.0)

100.0 (98.2 – 100.0)

1.00 (0.90 – 1.00)

0.00

EP-JV

71.9 (58.6 – 71.9)

98.1 (95.3 – 99.5)

0.76 (0.58 – 0.84)

1.99

EP-SR

62.5 (48.4 – 71.7)

96.8 (93.8 – 98.7)

0.65 (0.46 – 0.77)

3.36

EP-JV and EP-SR

75.0 (60.3 – 85.5)

94.8 (91.7 – 97.0)

0.70 (0.52 – 0.82)

5.47

  1. *When applicable, 95% confidence intervals are indicated in parentheses.