Figure 3From: Promoter hypermethylation of Wnt pathway inhibitors in hepatitis C virus - induced multistep hepatocarcinogenesisSFRP2 promoter DNA methylation analysis. Box and whiskers representation of average DNA methylation percentages at SFRP2 promoter region. Methylation levels increased in a progressive fashion that coincided with the progression of liver disease from chronic hepatitis to HCC. Significance of difference in methylation level calculated by Mann–Whitney test (p values) are shown where relevant. For more detailed information about group-wise comparison, see Table 3. N = Normal, CH = Chronic Hepatitis, LC = Liver Cirrhosis, HCC = Hepatocellular Carcinoma.Back to article page